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Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: a possible role for lithium antioxidant effects

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These medicines include tricyclic anti-depressants (amitriptyline), serotonin-noradrenaline reuptake inhibitors (duloxetine and venlafaxine), and selective serotonin reuptake inhibitors (fluoxetine and paroxetine)

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In low- and middle-income countries, access to advanced therapies like biologics is limited, with only 10 - 20% of patients able to afford treatments (7) costing $20,000$50,000 annually, exacerbating health disparities (5)